Yellow weather warnings were put in place by the Met Office for torrential rain across the east coast of England. However, those warnings have now been upgraded to amber warnings in Sheffield and Huddersfield.
The Met Office has warned that homes and businesses in Hull, Middlesbrough, Lincoln and Scarborough are likely to be flooded which could cause damage to some buildings.
Flooding and deep flood water has now been deemed “likely”.
Delays to trains and buses are also likely across the northeast of England.
A yellow weather warning is still also in place for north Wales with Conwy and Wrexham to experience “heavy and persistent” rain between 9am and midnight on Thursday.
The Met Office said “prolonged and heavy” rain throughout Thursday and into Friday could see rainfall of 80millimetres (3inches) in some areas of the north of England.
In other areas, 70millimetres (2.7inches) of rain is expected for north-facing hills, especially in the yellow warning area of Wales.
Some areas are also expecting 30millimetres (1.2inches) of rain, according to the Met Office.
Met Office meteorologist Aidan McGivern said: “There is a risk some places will see significant amounts of rain, particularly the higher ground of North Wales, the Pennines, the North York Moors and the Peak District.”
Coastlines along the English Channels will be the worst affected.
Rain has also been forecasted for the east Midlands but these showers will push northwards in the afternoon.
The evening is likely to be more dry in the area.
There will also potentially be some localised flooding caused by heavy rain in the east Midlands.
The nation has been encouraged to wrap up warm over the next few days as frost is likely in central and northern parts.
Herefordshire could see temperatures drop to 1C (33.8F) and Oxfordshire could see temperatures of 3C (37.4F).
Met Office weather spokesman Oli Claydon told The Sun Online: “It will be a chilly night, certainly. Wrap up warm.
“There will be a few scattered showers. Take a look at the weather to see if you are going to need a warm coat or a waterproof coat.”
He added: “Quite broadly, across the UK it continues to be unsettled.”
Weather warnings will be updated on the Met Office website.