The Met Office has put three warnings in place for snow and ice as wintry conditions blanket the nation. Scotland will see the most adverse weather as well as areas of north England and Wales.
Areas of Manchester, Stoke, Liverpool, Leeds and Chester and towns near St Asaph will be hit by icy conditions which could cause travel chaos.
Roads and railways are likely to be hit with longer journey times on roads and public transport.
The Met Office has also warned that injuries from slips and falls on icy surfaces could occur.
While yellow warnings for snow suggest there could be power cuts and faults to other services such as mobile phone networks.
Scotland and northern areas of the UK will see temperatures drop to around -8C (17.6F) going into early Tuesday morning.
The outskirts of London will see temperatures fall to near freezing.
Meteorologist Alex Burkhill said: “It is quite likely tomorrow morning that lots of people will have to scrape their cars and that kind of thing.”
The nation’s coldest night of winter has been -10.3C (13.46F), while the coldest night this year was -7.9C (17.78F).
“For the rest of the week, we’ll see a gradual increase in temperatures to around 13C (55.4F).”
The Met Office said: “Frequent showers will affect the northwest of Scotland during the rest of Monday, overnight and through to late Tuesday morning, falling as snow away from the western coastal fringes.
“Some spots may see accumulations of 1-3 cm below 150 m, with more widely 5-10 cm above 150 m.
“Strong winds may also bring temporary blizzard conditions in association with the showers at first, though winds will ease overnight.
“In addition, icy patches becoming widespread overnight away from western coasts.”
A further warning is in place until 11am on Tuesday.
The agency said: “An area of sleet and snow is likely to move eastwards overnight, followed by a few wintry showers. Surfaces then freezing, leading to icy stretches.”